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BHB provides energy when not enough carbohydrates or sugars have been eaten. BHB can also be made in the lab and taken as a supplement. In the body when fat is broken down, BHB is formed. It provides an alternate energy source for every part of the body, including the brain. Of the three ketone bodies produced during ketosis (BHB, acetone, and acetoacetate), BHB is present in significantly higher quantities in the blood.

BHB is one of three ketones the body produces during states of fasting or through low-carbohydrate, high-fat diets. In both contexts, the body naturally changes its primary source of energy from glucose (provided by carbohydrates) to stored fat.


Keto diets elevate BHB and promote weight and fat loss. Exogenous ketones also elevate BHB concentrations with the potential to protect against muscle loss during caloric restriction.